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1.
A string of noises emitted by retards when attempting to say "Hello".
A Homie: Yo yo yo, whaddup ma nigga.
Me: Shut the fuck up before I shoot you in the head (again).
by Spatter Artist February 19, 2006
 
2.
another way of saying wassup, or hi
"ey yo dawg how u been?"
by Diamond Princess April 04, 2003
 
3.
a slang term invented by george when he was sleeping in the middle of the night and woke up going yoyoyoyoyo and falling back to sleep again
man one:yoyoyoyoyoyoyoyo yeayeayeayeayeayea
man two:yoyoyo
by i am bilbobaggins April 28, 2006