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a strain of herpes that effects a person by making their mouth frequently dry.
tony: goddamnit why is my mouth so frequently dry?

bill: oh it seems that you may have yerpi's
by beaches&shores December 06, 2010
a type of herpes that effects you by making your mouth become dry. This can occur at any moment, and is very frequent.
Andrew: Ever since i had sex with that taiwanese hooker why my mouth has been so dry. it happens very frequently.

bill: O it sounds like you have yerpi!
by beaches&shores December 06, 2010