Top Definition
Often mistaken for being hydrocodone bitartrate syrup, yellow tuss is actually refering to tussionex periokinetic syrup which is a prescription cough syrup that is a very distinct shade of yellow. If i had to choose between the hydrocodone and tussionex, it would be tussionex hands down. woooo that is good stuff.
After i took a swig of that yellow tuss, i was feelin gooder dan a motha fucker.
by CPhT April 03, 2007

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