In Rochester, upstate New York, c. 1999, the sound of a two year old baby girl trying to say "I love you".
Father: Say, "I love you".
Daughter: "yayyo"
Father: "Yes, I love you".
Daughter: "yay yayyo".
by AdPaid_Marty July 03, 2010

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Top Definition
Slang for good azz cocaine.
Jeff sniffed the biggest line of yay oh I have ever seen, it was the size of a babys arm.
by B-Diddy February 13, 2003

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Slang for Cocaine, commonly used by Hispanic people. Was popular in the 1980's.
Me and my spic friend Manuel used to snort Yay-Yo in Miami in 1985.

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Cocaine often referred as blow, toot, snow, clean, white
lady, the albino. it is snorted inthe nose it goes for about $40 a gram.
All day I be slangin yay-yo
by Patrick Hughey November 24, 2006

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See Cocaine
Slang term which means cocaine
"yo, do you got that yay-yo?"
by zer0skill July 06, 2006

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spelled like this by dumb ass bitches - should be llello
i'm a dumb ass bitch and i'll buy a teener of yey - yo from justin the fuckin mann for 200 bills
by justin the fucking mann July 14, 2003

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