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Commonly used by people from or around the Detroit area. It is really suppose to be pronounced "Wut Up Though" but is said like Wut up 'Doe', it's just a phrase used by many detroits to say wut up.
*CHRIS WALKS INTO A GAS STATION*

Chris: Wut up doe!

Arab behind the counter: Wut up doe my baby!

Chris: Shit chill'in let me get too loosies.

Arab behind the counter: Ight my baby be safe.
by Trap star 313 January 20, 2007
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2
"What's up brother?" in terms used in the movie 8 Mile
*at seeing your close homie at any location*
-Wutupdoe
-Nutin' chillin, nigga
by T. Herm October 08, 2007
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