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1.
Commonly used by people from or around the Detroit area. It is really suppose to be pronounced "Wut Up Though" but is said like Wut up 'Doe', it's just a phrase used by many detroits to say wut up.
*CHRIS WALKS INTO A GAS STATION*

Chris: Wut up doe!

Arab behind the counter: Wut up doe my baby!

Chris: Shit chill'in let me get too loosies.

Arab behind the counter: Ight my baby be safe.
by Trap star 313 January 20, 2007

Words related to wut up doe

chill'in doe though up wats good what up wut
 
2.
"What's up brother?" in terms used in the movie 8 Mile
*at seeing your close homie at any location*
-Wutupdoe
-Nutin' chillin, nigga
by T. Herm October 08, 2007