1.) Tired, exhausted. See worn out.
2.) To overstay one's welcome.
3.) To use something to the point it no longer works or becomes ragged/shoddy.
4.) To completely, utterly, and totally beat someone up.
Example 2: "After several lame jokes, Bill wore out his welcome at the company picnic."
Example 3: "If you keep wearing that shirt it'll be wore out in no time."
Example 4: "Some guy insulted my girlfriend and got his ass wore out for it."