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1.
the ability to have countless hours of drunken sex without the ability to have a male orgasm. Also know as a "lost cause"
man i was banging her for hours and never could nut, i guess i had a case of whiskey balls
by sulaboy June 15, 2007
 
2.
the saturation of one's testicles in sour mash whiskey.
After passing out in the chair next to the campfire with an open bottle of Jack in has hand, Chuck had a nasty case of whiskey balls.
by Charles Rice June 27, 2006