1. A query as to one's preference, specifically in regards to consummable goods
2. a query as to one's preference in alcoholic beverage or drugs
3. a question of one's preference in women
1. Alfred: What's your poison?
Rudyard: Give me a slice of pepperoni, beyotch!

2. Alfred: What's your poison?
Rudyard: Give me some mother fuckin' crack!

3. Alfred: What's your posion?
Rudyard: I likes me the big-titty bitches yo!
Alfred: Word!
by puma_blues March 29, 2004

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug
Top Definition
What do you want to drink.
Bartender asks a patron, "What's your Poison?"
by DD March 29, 2004

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug
What are you drinking? Usually in terms of alcohol
"Whats ya poison?"
"Tequila slammer"
by xx-rach-xx March 28, 2004

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug
usually said by sleazy guys in bars as a way of asking to buy you a drink
"hey...What's Your Poison"
"baileys now feck off"
by Beaky February 29, 2004

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug