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1. what's your damage?
"what is your problem?"

basically the same thing, except replacing problem with damage makes you sound twenty years out of date
Barack: "Senator McCain, what's your damage?"
John: "My damage, Senator is you!"
2. what's your damage?
A sarcastic way of asking someone about the mood they're in. Was coined in the 1988 teen drama, Heathers.
From Heathers (1988):

Heather Chandler: What's your damage? Brad says you're being a real *kuse*.
Veronic Sawyer: Heather, I feel really sick, like I'm gonna throw up, so can we please jam now?
by TommyT Aug 2, 2005 add a video
3. What's Your Damage?
Made famous by cult-classic movie 'The Heathers', a black satirical portrayal of an American high school featuring three girls called Heather.
"What's your damage, Heather?"
4. What's Your Damage?
A phrase used by nimrods who want to be "up beat" with the millennium’s technology advance by switching a technical term into a harsh question when they could just ask you nicely if something was bothering you.
"Geebuz d00d, what's your damage?"
"Mom, cut it out, you're scaring little Timothy."
by Phatal Aug 29, 2004 add a video
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