Similar to what it do but asking of possibilities in the future not whats going on in the present. Its a greeting like, "whats up?" or "how are you?" posing the question, "what can we make of this?". Its not asking "whats happening?" or "what will happen?" but "what can happen?". What can we make of this opportunity which is the present?
What it can be fellas? Are we gonna make this money or what?