Top Definition
1)An affirmation used to express one's own "down for whatever" attitude.

2)A greeting.
EX.1
Gentleman #1: Ay bro, I'm bout to head out to the club tonight and get up on these hoes. You rollin'?
Gentleman #2: Shiiiit, w'sup wit it?

EX.2
Gentleman #1: Hello sir, good day to you.
Gentleman #1: W'sup wit it?
by Jesus Juuce December 05, 2005

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