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2.
Quite literally change, or chaotic nature. Vicissitude would be used to describe the emotional state of mental patients or the chemical properties of nitro and glycerin.
Vicissitude is a word that is used mainly to belittle others in that very few people know it's meaning.
by Nathan July 17, 2004
 
1.
a natural change visible in nature or people
by BLED FOR DAYS December 03, 2002