the illness that causes someone to be a big baby. The cause of constant complaining or pouting.
Samantha gets a bad case of Vagisitus when I don't answer her phone calls.
by tim bernard November 23, 2009
A sick or infected vagina.
I was gonna go down on her, but when I pulled her pants down it was obvious she was suffering with vagisitus.
by joeking November 18, 2007