When the fold in the pants near the crotch form a vagina like crease.
Look...Mikey has his vagina pants on again. and boy does his ass look hungry
(Noun) To behave in a weak-kneed, cowardly, panicky, or otherwiaw pussy-like fashion.
1.) When it became apparent that simple-minded belligerence would not help him in his war against America and other Free-minded peoples, Osama Bin Laden put on his Vagina Pants and turned to hiding in caves.
2.) Osama Bin Laden is a Vagina Pants.