when you go on vacation and all the girls appear to be hotter than the girls in your hometown, usually because you're only paying attention to the hot ones. (applies to day trips as well)
A: Dude I got Vacation Syndrome cause the ass here is ridiculous!

J: lol did it give you yogurt pants?

A: You know it, there are NO ugly chicks here!
by goldenwings173 January 28, 2014

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