Top Definition
a virus that attacks your penis and turns males into whores until they've stuck their genitalia into every crevice available.
usher. he has the usher disease.

hey look at that guy fucking a toaster! he's got the usher disease.

russell brand has the usher disease.
#usher #disease #russell #brand #toaster #penis #aids #crevice #whore #genitals #purple #available #i likes rocks
by the green goblinator September 07, 2008
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