Top Definition
The vernacular for the outpatient surgery to check one's colon for pollops. Often referred to as a colonoscopy by professionals. The term can also be used to describe the procedure required to remove office brown nosers.
Geez, now that I've turned 50, I've got to go get an upthebuttomy.

Eric is such a brown noser that I'm going to have to get an upthebuttomy to remove him from my ass.
by Bubba Abdul Ledbetter September 02, 2009

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