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verb

to place someone in an awkward or unpleasant situation by guile or deceit; to play emotional games with someone prior to letting them down.
*sighs* "I have been waiting here on this park bench for two hours, and she hasn't turned up. I guess I've been set up."
set up by benbisley March 8, 2010

somebody set up us the bomb 

Famous line from famously remembered badly translated japanese video game Zero Wing, turned internet phenomenon with many different parodies of the original sega game
Narrator: In A.D. 2101, war was beginning.
Captain: What happen ?
Mechanic: Somebody set up us the bomb.
(spoken in the Flash animation as Someone set up us the bomb)
Operator: We get signal.
Captain: What !
Operator: Main screen turn on.
Captain: It's you !!
CATS: How are you gentlemen !!
CATS: All your base are belong to us.
CATS: You are on the way to destruction.
Captain: What you say !!
CATS: You have no chance to survive make your time.
CATS: Ha Ha Ha Ha ....
To kill somebody or to arrange the murder of somebody.
Do you know who set up Vancouver Kingpin Sandip Duhre? Ya Robby Alkhalil did it, he got convicted for it.
Set up by AntiGang October 24, 2014

Set up chips 

When you're having friends over and you wanna make em something real nice to eat. So you get some of those taco chips shaped like teeny tiny bowls and you fill em with salsa and then serve em up. Everybody gets so happy that every time they see you they ask for some more set up chips.
Lynn: Hey Donna I was thinking of coming over later. You think you could bust out some of them set up chips?

Donna: It ain't a party without some set up chips.

Lynn: Set it the f-up!
Set up chips by Nurselynnski December 2, 2013

somebody set up us the bomb 

A poor Japanese-to-English translation in the 1991 Genesis game Zero Wing, which is also famous for the origin of "all your base..."

It is commonly incorrectly stated as "somebody set us up the bomb". Clearly, the up comes before the us, although the resulting diphthongs makes it more difficult to say.

72reality: LOL SOMEBODY SET US UP THE BOMB

838672cloud: Its somebody set up us the bomb, noob

72reality: fu kthx

Throwing up a set 

The act of flashing gang signs, most commonly by using the most ridiculous fucking hand gestures and/or figures... ever.
"Yo! He throwing up a set! He a blood! Bust a cap in that nigga! Peel his muffin-cap back blue!"