look up any word, like fleek:
 
1.
Usage: 1. up in here
2. up in this <noun>
Non-urban: "Gosh, I wish the landlord would fix the heat, it's freezing in this apartment."
(2) Urban: "Got-dayum!! Can't we get some hizzle up in this motherfucker?!?"
by bizook March 22, 2003
 
2.
An uneventful and boring pussy; one with which no 'curtains' or a hang-down are present. Resembles two hamburger buns smooshed together with no meat in the middle.
...that chick has some intense 'up-ins'...
by Neal Manchester January 19, 2011
 
3.
up in: (adverb) location of with which an object is placed and an action is occuring.
"Don't be puttin my name up in yo mouth!"
by shortbus January 05, 2004
 
4.
The act of violating one's personal space, often used with the verb "nosing"
My mom totally found my stash when she was nosing up in my room, now I'm grounded for life + forever. alternately That chick I met was hot, but then she started nosing all up in my sex life, and I don't want her to know that Jennie might have gonorrhea, so I slap her upside the head and she don't be nosin' up in anything.
by Jimbo December 01, 2003
 
5.
when a dick goes in your heiny

My boyfriend tried an up in.
by Vagina November 04, 2003