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1. up on blocks
UP ON BLOCKS - menstruating. i.e. Out of action, a bit like a car in a garage. e.g. "I don't think I'll be in luck tonight lads,the missus is up on blocks".

2. up on blocks
to rob someone completely unbeknownst to them, to steal everything from someone, to 'rob them blind'. to go behind someone's back when they least expect it and take as much as you can from them; the opposite of 'strongarming' someone.
"that nigga earl went off to work and me and flossy came through his crib, needless to say, we put that nigga up on blocks!"
3. up on blocks
the 28th day of a womans 'cycle'
she wouldnt let me fuck her coz she was up on blocks.
by jody Oct 30, 2003 share this add a video