a person who is forced to be the first to do something they don't want to do, but circumstances have left that person with no other options.
Kris: "no other medication has worked, I have no choice but to take this experimental drug. But, I don't know what the side-effects are. I don't want to be the example for others if something goes wrong. I am an unwilling pioneer."
Dave: that sucks man
a person who is forced to be the first to do something that they do not want to, but see no other choice.
no other medication has worked for me, so I have no other choice than to take this experimental drug. But, I don't want to be an example for others if it has some unforeseen side-effects. I am an unwilling pioneer. I don't want to be the reason that there is a disclaimer "may cause anal leakage" as a possible side-effect at the end of the commercial for that drug.