Top Definition
When you give a blow job to a guy named tyler; the jizz of a guy named tyler.
Girl : "Gimme some tylernol."
Tyler : "OK, get on yo knees bitch!"
by RTDeon April 10, 2008
1 more definition
The medication for any, and all crappy days.
Person 1: "Wow, this day has been so sucky and boring."
Person 2: "You should call Tyler and get a dose of Tylernol!"
by mastersoftheunderworld November 05, 2011

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