A Canadian term for a 26-ounce bottle of alcohol. The modern bottle is actually 750 mL (25.36 oz), but it is still commonly called a two-six nonetheless. (See also: two-four.)
I finished off a two-six of rum in one evening, and did not feel good the next morning.
The act of being extremely cheap.
That cheap-ass didn't tip again! He's always two-sixing me!