Top Definition
A skinny woman who was no breasts or ass.
Your girlfriend is like a two by four, skinny and flat on both sides.
by bfb August 23, 2012
1 Word related to two by four
Used by close friends to express that some one hot or good looking is near them. If they reply by saying two by four then they also agree that, that person is hot or good looking
Two by four over there. Your friends look at you and say Twobyfour
by Eric Gonzalez aguilar munoz June 15, 2008

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