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1.
An idiotic remark uttered by a twit who mistakenly believes he/she is being witty
Bill let loose with a string of twitticisms that proved he is a master of masturbatory thought, not an intellectual.
by deli-cut June 16, 2004
 
2.
Criticism of another person or group through tweets, on Twitter.
When the liberal tweeted his opinion on the issue, the fire-breathing conservative responded with harsh and typo-filled twitticism.
by HE AIN'T GONNA EMAIL YOU March 14, 2011
 
3.
A vacuous and yet allegedly witty status update.
‘I don’t follow his tweets – he writes nothing but twitticisms.’
by stipemeistercentral July 07, 2009