Top Definition
A male engaging in anal sex with another man. The "tube" is derived from the large amount of lube necessary to enter the anal cavity. Twisting a tube means literally twisting a tube of lube so that you get every last bit of lubrication out of it, those last few drops.
Yeah, I saw Jim leave with that guy.. whatever though, they're probably heading back to his apartment to twist a tube up.
by A - L - X May 20, 2007

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