Too exhausted to do anything, too wired to sleep.
I felt twired after drinking an espresso at 4:00 am.
To be in a combined mental state of tired and wired.
I see my colleague in the elevator on the way to the meeting room. I ask him how he is doing. He says, "I have been up all night to prepare this presentation for the board. I've been working on it non-stop for three days. I've been drinking coffees like a bandit to stay awake. I'm so toasted. I'm so wired, too. Man. Hell, I''m twired.
A combination of exhaustion and over use of stimulants resulting in a delirious state.
Pete: Dude I just worked a 12 hour shift and drank 3 redbulls to finish my 24 page paper.
John: You're going to be so twired.
Wired of off all things Twilight related.
Maybe you're up late at night into the early morning hours searching the internet for anything and everything Twilight related...Or maybe you can't stop watching your trusty Twi-DVD, either way, you're most likely Twired!