Top Definition
twilightcancer is a form of cancer contracted by high exposure to the toxic waste known as twilight. Also can be contracted by watching the movie and standing within 100 mile radius of the author of the piece of shit book and can be contracted from having intercoarse with the author or anyone who has it, it is both a cancer and a STD. can also be used as a adjective
twilightcancer (tw-ill-ih-gh-it_can-ser)

jim: last night, i had sex with linda.
bob: you do know she had twilightcancer right?
jim: fuck.

bill: i love twilight
steve: fucking twilightcancer
by 0mg toxic February 08, 2009

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