look up any word, like blumpkin:
 
2.
N:Twitter speak for people.
Them my mofo tweeples!
by BLuTink78 June 29, 2009
 
1.
People who use twitter.com.
All the lonely tweeple, where do they all come from? All the lonely tweeple, where do they all belong?
by BrianBCarter April 15, 2008