word used to describe some one who has had drugs and is feeling the effects.
Dam Johny only took one hit and hes tweekin out.
by Danielle November 29, 2004
actin funny; wildin' out; trippin hard
dude #1-daaaaag joe, I see horses in the mafuckin sky! On my momma check this shit out!

dude#2-that boy tweekin hard
by 74-BOSS August 09, 2005
meaning sprung, or obsessively in love with something or someone... :)
"uuuhhh, bitch yu tweekin, damn chill!"
by nicolebitchesz January 16, 2009
to modify something in order to make it functional
I'm tweekin this light socket into this lamp, it's really designed for a bigger one.
by susieq502 January 08, 2006
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