the nervous ticks or twitching one experiances as they come down from a crystal methamphetamine binge.
pulling hairs out of their face; picking at their face; picking their nose...
by a former tweeker November 28, 2003

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Can be a state of paranoia, Have to urge to hurt or kill somebody, Be Extremely mad (sometimes because of drugs or mental ilnesses)
Im going to Tweek on someone very shortly!

by Mike AKA TweeK February 06, 2007

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Generally used as a verb to refer to what a DJ does to the knobs on the mixer.
Did you see that DJ tweek the knobs?
Tweekin' the knobs!
by katze April 19, 2005

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to enhance
"Dude, check out my tweeked up motorcycle..."
by kevsgrl2004 June 09, 2003

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A mad individual who can cause pain to himself and not give a damn. the spawn of god and satan.

Will act as below:
Runs around fields on cold night, in only his underwear, smoking and screaming "I rape chickens". sleep talks about foursoms, chickens, wanting sausages, and aaarrghffejwfbisduf!!
by Ernie October 15, 2004

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to pinch or flick
I tweeked her nipple and she tweeked my clit with her tongue.
by Junebug January 13, 2004

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Noun. A boisterous dork, dweeb or nincompoop. An annoyingly loud twit.
Shut the fuck up you stupid tweek.
by E. Debs April 01, 2005

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to be messed up
"Man my arm is totally tweeked..."
by kevsgrl2004 June 09, 2003

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The Urban Dictionary T-Shirt

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The Urban Dictionary T-Shirt

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