A singular noun referring the buttocks or ass. Also may be used as a verb, meaning to stick your butt out.

Org: Homestar Runner's Strong Bad Email 147
n: "Strongbad, you're a horse's twees."

v: "OK everybody now twees it out!"
by racartier March 09, 2006

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Something that is cute ironically, with the irony taken out
The opening band wore all pink and danced joyfully, but the headlining band was even MORE twee!
by Susanarusan December 01, 2007

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Someone insanley cute and adorable. Probably too good to be true. They make everyone smile from ear to ear to the point that it hurts. They can make anyone laugh and know just what to say. They always dress nice and are absolutely gorgeous
Jimmy: "Lacey is just so damn cute and nice"
Jimbo: "Yeah Lacey is so twee"
by Hobo-Vampire May 26, 2009

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A hybrid of the words "tiny" and "wee" used to describe states of smallness.
"That twee bastard stole my hot dog!!!"

"Girl A: I hope your boyfriend dies of rectal cancer!!!!

(silence)

Girl A: Too much?

Girl B: A twee bit."
by Little Darling January 03, 2010

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someone who is adorably sweet almost too sweet, sometimes hippie like. It's also a spin-off from the indie style they like being unique but not "in your face unique".
Twee people always love to make people smile.
They usually dress mod-like and wear dresses, flowy shirts, band shirts, bows, plastic jewelry, and little kid treasures.
-Twee people are alowed to listen to anything they please! but they usually like chill music, indie rock, and techno.
girl 1: Oh my gosh did you see Marcy's dress?!?!
girl 2: I know it's so cute and mod. she totally works her twee-ness
by katiecarrot July 10, 2008

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noun - twee is short for tweak, which is speed, and almost always refers to crystal meth, but ritalin, aderall, and some other drugs are also called twee
"would you like a bump of twee?"
by Dr. Lovechilde December 27, 2009

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-- of, or relating to, something of little value that can evoke such a delighted sound from someone of little intellect.
Those crocheted bun warmers are too twee for words.
by mbhiii November 26, 2006

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