2.(v) when in sneak mode in the game: Elder Scrolls, Oblivion, you attack in hand-to-hand mode.
3.(v) any gesture involving the first 2 fingers on any hand jabbing forward, mimics the female masturbation or anal motion and is considered worse than the finger
2. Todd totally pulled a twee on that rat in the Imperial City Sewers.
3. When Lindsey saw Kacie she quickly shouted, "Bitch!" and shot her the twee.
In American English it often refers to a type of simple sweet pop music, but in British English it is used much more widely for things that are nauseatingly cute or precious. It comes from the way the word sweet sounds when said in baby talk.
Jimbo: "Yeah Lacey is so twee"