a tweaker is simply a weirdo, from that weird girl who stalks you, the weird witch lady who lives at number 3 to that crazy old guy with the massive beard who rides his bike around all day muttering. its useful to have in the vocab as it can be shouted with no risk of insult to the tweaker in question. by streachin the sylables it can be made into an almost bird like cry. if u like
tweeeeee-kaaaaaahh
"oh my god, this guy is a fucking stalker, what a tweaker"

"shit dude, did you see that matey wearin girls clothes, what a tweeker"

"whos that tweaker on a microscooter"
#weirdo #freak #wrongen #fuck up #tizzard
by purv of the gore April 26, 2007
A word used popularly in Philadelphia, Pa to describe female dogs who get “smutted” around by a group of men. The men are either friends, cousins or even siblings maybe complete strangers but that's rare with Tweaks. Tweakers are often exposed on the Tweaker List page via Facebook. Tweakers are not aware that they’re tweakers, until they appear on the Tweaker List. However, 99.9% are still in denial after being featured on every list. You can always find a Tweaker on Broad & Olney, King of Prussia, and Franklin Mills. They're in there like swimwear.
Girl: I'm not a tweak, I'm 15 years old and I let 5 guys hit.
I only sucked 14 dicks this year. Yes, I'm on the tweaker page, but these girls just hating on me because I had sexual intercourse with their boyfriends.

Boy: Your the true definition of a tweaker.
#smut #slut #whore #std #aids #herpes #crabs #syphilis #gonorrhea
by Never Lying September 13, 2010
being a dumb ass
jim your a fucking tweaker you know that
#tweaker #tweker #tweakr #dumbass #funny
by tweaker101 July 19, 2010
A Noun. A GIRL OR BOYTHAT IS KNOWN FOR SLEEPING WITH OR GIVES ORAL SEX TO PRACTICALLY THE WHOLE NEIGHBORHOOD.

A Noun. A GIRL OR BOY THAT IS KNOWN FOR SLEEPING WITH OR GIVES ORAL SEX TO NUMBERS OF PERSONS THROUGHOUT THE CITY.

TWEAKER IS USUALLY USED TOWARDS FEMALES, BUT IT IS NOT UNCOMMON TO USE IT TOWARD A MALE. BOYS ARE USUALLY CALLED THE "BURNING BOYS", THE EQUIVALENT OF "TWEAKER".
*SEE "BURNING" 2nd and 3rd definitions...*
JESSICA SIMPSON SLEPT WITH KIM KARDASHIAN'S BOYFRIEND REGGIE BUSH.

KIM -"Jessica slept with my boyfriend, and I heard that she slept with Common, Kanye, and Usher, and gave Ray J, and Nick Cannon oral sex,... She is a TWEAKER!!!"
#burning #whore #slut #dick sucking lips #smeeze
by ANCIENTCHINESESECRET93 May 18, 2010
Someone with a methamphetamine who is usually a theif.
That fucking tweaker stole my lighter
#junkie #theif #dope head #crackhead #buster
by Dustin Hubiak June 01, 2007
1. A person who customizes an operating system, a.k.a. MS Windows or Linux.
2. A person who speeds up their computer. See also overclocker.
1. You know Ken, always changing his settings. Such a tweaker, really.
2. Hey, that Dave guy burned out his CPU again, tweaked it too much.
by Toba September 22, 2004
a man/woman who does an action that may seem strange or efed up to the people around them
hahaha look at that fukin tweaker. haha wtf is he doing?
#tweak #crack #tweaker #crack head #efed up
by l)yl_A/V February 14, 2008
1 A thing you hold and point at the t.v. to change channels.
1 'Oh no, it's Mandelson (or other politician of choice), pass the tweaker quick.'
#remote #tuner #button-stick #thing #mandelson-remover
by Sue d'Aunim December 06, 2009
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