look up any word, like fleek:
 
6.
to screw up something.
he tweaked his wrist when he fell off his bike
by Gordo352 April 03, 2006
 
1.
To be high on methamphetamine. NOT hallucinates
He's so tweaked out.
by kush_ March 16, 2005
 
2.
Out of sorts, or on drugs.
He was so tweaked that he didn't know whether he was coming or going.
by Billy March 11, 2003
 
3.
An idea that just appeared. When your mind brings a solution to something into your thoughts.
In a conversation with someone you are trying to pick out a solution to a maths sequence and suddenly your brain recoginses the pattern........you tweaked to the idea being used.
by Mr Berry, Moon March 14, 2012
 
4.
1. Become influenced by drugs or Foreign substances...in a bad way

2. IT. To say you fixed something on a PC or Server when you really broke it, and really broke it goood.
1. maaaan... I'm so tweaked out, I vomited all over myself while driving on the Motrway

2. IT. Tim Black the ginga...grrr
by Bob is u're auntie August 23, 2008
 
5.
1. Jonesing.
2. Completely disoriented.
"Gurl....I'm so tweaked I can't even see straight."
by Peter Tweaker August 06, 2003
 
7.
angry, irritated, pissed
She's been ragging on me all morning. I wonder wahr she's so tweaked about.
by Malkim El-Shabazz September 24, 2003