1)A derogatory term for a transsexual woman, which implies she isn't a "real" woman. It is most commonly used in porn for straight cisgender men; also used in dehumanizing trans women for joke or violence.

2)A term used to insult a cissexual/cisgender person by implying that ze is a trans woman.

3)An affectionate term for any trans-identified person; language reclamation from 1st term. Most commonly used by young trans people, especially trans men & masculine genderqueers, among whom the "language reclamation" use started. Trans women have argued that this use of the term is appropriation, not reclamation, as the derogatory use of the term has almost exclusively focused on women, yet 'reclamation' efforts have largely been steered by men.
1 & 2--see "definitions" by "mike" (and variants).

3)Hey, did you hear, the Tranny Roadshow's playing at Genderblur tonight!

I thought this was a queer/trans dance. There's, like, three trannies here. They don't even have gender neutral bathrooms!
by transbitch October 31, 2007

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In mechanics, a vehicle's transmission.
Pull that tranny so we can overhaul it.
by Downstrike June 04, 2004

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Stupid ugly as fuck math teacher that falsely accuse's students of being on drugs
My math teachers such a tranny
by Anus crusher March 21, 2017

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A very offensive slur to transgender people.
Guy 1: Hey look at that ugly tranny over there! Guy 2: May be the ugliest tranny I've ever seen.
by MessedUpSoul February 13, 2017

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short for Transplants: a term used frequently in Santa Cruz to describe people that were not born and raised in town aka not locals. Typically used by the surfing community
All the rich tranny valleys moving in to the neighborhood are pushing the locals out.
by sam April 13, 2005

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A guy who likes to wear womens clothes and make up. Could or could not desire to be a woman and have a sex change.. some get it done. some don't. This isnt just a one time thing this is a way of life for us. I found another fellow tranny online through a support group and we are now a happy couple. 'Heart' you Sal.
Sal & Mike, both pre op tranny's found eachother through online personals.
by Love your tranny brother, Mike September 11, 2007

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Tranny - Pronounced Trah-Nee ..

#1 The transmission in an automobile. Short for transmission
#2 A man who dresses as a woman. Short for transvestite
I was driving to school this morning and I had the worst day, First my tranny went out then it turns out the hooker, I picked up was a tranny !
by OG$MIKE August 21, 2016

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