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2.
Incredible synthetic opioid, used for moderate to severe pain. Normal recommended dose is around 1 to 2 50mg tablets. however if this were increased to 4, making 200 mg total, effects similar to oxycontin are felt. Used to treat pain from trauma or surgery. Also used for post-operative pain management in animals. The pleasant, relaxed high from a 200mg dose usually lasts around 6 hours, depending on the weight of the user.
I got some tramadols for my leg, and man, i was fucked up all day.
by VagTasticVoyage November 13, 2008
 
1.
HELLA good narcotic that works on the opiate receptors in the brain similar to vicodin. Although it affects these receptors in a less euphoric ammount, the drug converts itself in your body into a seperate drug, which can last upwards of 8 - 12 hours.
dude i popped those tramadols and tripped all day

man hook it up w those trammies
by TreflipTony January 04, 2008
 
3.
A synthetic "poor man's" opioid. Acting almost exclusively on the mu-type opioid receptors (1 of 4 types) it is considered milder and less addictive than most other natural and semi-synthetic opioids. Used to treat moderate pain, it is most commonly sold under the brand name Ultram.
Its recreational use is limited, due to its relatively low strength, and higher incidence of side-effects when compared to other opioids. Many opioid users refuse to buy it, and its street value usually won't break $1.
It is still an opioid nevertheless, and can produce a relaxing high at upwards of 50mg, but its lesser effect, nauseating side effects, and longer reaction time makes it undesirable for most users.
I popped two 50mg tramadol tabs a few hours ago and now I'm puking my guts out! What the fuck?!
by WNC July 31, 2012
 
4.
A strong painkiller and synthetic opoid (meaning it acts on the opiate receptor). Often used recreationally by those lucky enough to acquire it. There are reports that a standard medicinal dose of 100-200mg provides a gentle mood increase and relaxed high. I personally have never found this quantity particularly effective but doses of over 500mg, often combined with huge doses of caffeine, have provided some of the best moments of the year so far. At these much higher dosages (400mg+), the high is unmistakable; characterised by a huge mood increase, hyperactivity, increased enjoyment of music and the urge to run around pretending to be an aeroplane (literally). The high (at all doses) is stated to vary between about 6 and 12 hours. The larger doses tend (without guarantee) to last longer but obviously this is quite a long high by all means.

When combined with a decent caffeine kick, you can reach a point at which you're shaking hard and constantly all over, you can't stand still or sit down, time seems to slow down in places and your inhibitions are all but gone. This is as tempting to some as it is off-putting to others. All I can say is that from personal experience it feels good, man.
Elliott: I just made some more tramadol tea yo. Man, that shit's good.

Elliott: Gonna rail 10 tramadols and get wasted, who's in?
by [TPx]E! November 23, 2009