Top Definition
A condition of the male genitalia whereby the appendage is of an extreme offensive odor due to poor personal hygiene, thus rendering the possibility for felatio or any form of uncovered contact virtually impossible for a prospective partner to withstand. Derived from the medical term Toxic Shock Syndrome.
Man, I heard your bro hasn't had much one on one action of late.

Yeah, what do expect from a guy with toxic cock syndrome.
by froggystomp September 15, 2010
1 more definition
When your boyfriend wants to have sex thirty times in one day, you get Toxic Cock Syndrome.
Would you get that thing away from me, I've already got toxic cock syndrome.
by goofilicious May 23, 2011

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