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1.
The inability of a heterosexual man or lesbian to think clearly since his/her cognitive faculties are being hindered by noticeable breasts.
May be either used as a noun for the person or an adjective for the condition.
Look how Steve's mind is mush while the Girls Gone Wild commercial is on--he is a huge titwit.
by Adam August 01, 2005
 
2.
Some nitpicker who ardently tries to supersede keeping abreast of lesser notorious though ostensibly mpre glorious nitwits.
Rather keep your wits 'bout you than moaning like a proper titwit.
by Hercolena Oliver October 02, 2008