Top Definition
1.One ruining everyone elses fun.

2.Also could be used by women describing what a cock blocker is to men. A woman stopping another woman from getting laid.
1. john: "hey we should all burn down that church!"
sarah: "no, that's a bad idea people will die!"
john: "don't be such a titty buster!"

2. "I could've hooked up with John, but his ex wouldn't leave us alone. She was being a total titty buster."
by Famousanus May 21, 2006
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