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9.
Expression to describe when a person or activity has run its course and met its end. Dead. Finished. Done. The expression is thought to have originated from military pilots when reporting from the air the visual status of other planes that had gone down and met their end, and in doing so on the way down or at their final resting place (or both), were often times "upside down" with their wheels pointing up rather than down as they operationally should have been. When seen from high above upside down with belly and wheels pointing up, they were described as they appeared....."tits up".
Hey...are the Cowboys going to the Superbowl or not?

What? No man....they lost last Sunday. It's over. They're tits up dude.
by DallasBB May 09, 2011
 
1.
broken; dead in the water, floating
well that project really went tits up.
by Anonymous July 26, 2003
 
2.
A word used to describe something that has broken or someone who is dead
Damn, my graphics card just went tits up
by God September 29, 2003
 
3.
description of a situation where everything has gone wrong, sometimes disasterously wrong
Those two teenagers were almost killd in that tits up car wreck.
by aaron January 01, 2004
 
4.
Military slang for "Total Inability To Support Usual Performance".
Inoperational, regardless of the reason, on either a temporary or permanent basis.

My cell phone battery is almost titsup, and I left my charger at home.

His cell phone was titsup after his ex tossed it into the hot tub.
by reverb November 20, 2005
 
5.
broken, fucked up, shit the bed, passed out.
Charolette was pissed off because her dildo went tits up.
by Anonymous November 21, 2002
 
6.
Whens somethings gone wrong/screwed up
Its gone tits up
meaning its gone wrong, its not working. something like that
by Arkz September 12, 2004
 
7.
Total Unconsciousness. a term used in the military to describe the final stages of several medical conditions (heat exhaustion, heat stroke, chemical exposure, etc.) Also called tango uniform using the military radio phonetics. "Tits up" is the slang version.
You'll go tits up if you don't get injected with atropine within 10 minutes of exposure.
by goopup January 26, 2006