An "it" who is known as a "hoe". Goes by the name Tissue, possibly has AIDS/Herpes from sucking the GMs dick, in a game called "OdinMS". An attention whore who has no life, googles pictures of "models", and possibly claims that it has a boyfriend in real life.
Who be tissue?
A girl who stands near kerning city and waits for the GMs to log on, so she can get some penis.

What the fuck why do you guys call it an "it"
Possibly, because there are no real girls on the inter web.
by LOLBBQSAUCELOL January 01, 2008

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Top Definition
your best friend when your nose needs some lovin'.
"hello tissue. i'm sick. come here and give me some nose-lovin'."
by jason January 08, 2004

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used after jacking off to help clean up cum
fuck, where are the tissues, i have jizz all over my hands
by edwin gaffney March 07, 2006

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According to dictionary.com, "A soft, absorbent piece of paper used as toilet paper, a handkerchief, or a towel." IT is generally used to wipe one's nose when snot collects inside one's nostrils. Most tissues can be purchased at your local supermarket or pharmacy, or if you live in a small town at your local general store. Tissue paper can also be used for craftsmaking according to alibaba.com, and Kleenex is the most popular tissue company.Then again, does anyone honestly care what the definition of tissue is? Does anyone actually not know what a tissue is? Sheesh
Dusk,I wiped my schnozzola with a tissue and proceeded to bed.
by ijustlivehere January 16, 2006

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To be used after long nights of halo'ing (see Halo) or pr0ning (see pr0n or circle-jerk). Note: Never to be used on the nose, as your roommate will often use it after halo, and put it back in the box. Thanks Justin.
My nose is running. I need a tissue, where is that box of tiss- oh god, there's jizz on my nose. Where's Justin?
by hobo.breakfast May 03, 2006

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An aggregation of morphologically similar cells and associated intercellular matter acting together to perform one or more specific functions in the body. There are four basic types of tissue: muscle, nerve, epidermal, and connective.
The destruction of solid tissue resulted in a collection of pus around the wound, also known as an abscess.
by blammord March 23, 2006

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A suitable nickname for any boy that struggles with cope with the stresses that an average four year old girl would cope with.

Someone who crys when the going gets even a tiny little bit tough.
D: I can't handle the stress! I'm too busy!

T: STFU, Tissues. Take it like a man.

D: *sniffles*
by The _ Knowledge November 17, 2010

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