Top Definition
A situation whereby things get going so fast or are so bad that the entire operation project or relationship fall apart in a catastophic manner.

When the adjustable rates mortgages reset the wheels came off the bus. Many Yuppies who had purchased large expensive homes now found themselves in foreclosure unable to sell their homes or make the now huge payments in a declining real estate market.
by Norbert Young March 25, 2007
5 Words related to the wheels came off the bus

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