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1.
A polite way of saying, "I don't care."
Dude: I bought this really pimped CD.
Girl: That's nice.
by Nick March 05, 2005
 
2.
A common response to a comment which you find uninteresting, boring, or you are just downright not in the right mood to care about.
Person 1: Dude, I just did a quadruple backflip on my unicycle!
Person 2: That's nice.

Person 1: Hey man, I asked out this chick, and she rejected me.
Person 2: That's nice.
by boogerh7 January 25, 2011
 
3.
A polite way of saying, "Fuck you!"
Southern Belle #1: "Look at this ring my husband bought me!"
SB #2: "That's nice."

SB #3: "Look at this fur coat my husband just gave me!"
SB #2: "That's nice."

SB #1: "Why didn't your husband get you anything?"
SB #2: "Well ...he did send me to finishing school..."
SB #3: "Why'd he do that?"
SB #2: "...So I could learn to say THAT'S NICE instead of FUCK YOU!!!!" :)
by Silver415 November 05, 2012
 
4.
people like me and my friend use it quite often and it sounds funny. Its used for generally when your not interested or you dont want to know.
Boy: i won a trophy from football
Girl: thats nice, i won a rubber dick to give to you for yah birthday

Friend: i went horse riding on saturday
Girl: thats nice, i went up yah fanny to pluck your pubes on the same day

Smelly person: you cant afford new trainers
Girl: thats nice, you cant afford a shower cos you stink of fishy fanny

Little kid: I hit you on the head with the ball
Girl: thats nice, i hit you in the keys when it splatted with blood
by ronnie1997 August 03, 2011
 
5.
Cleveland Brown ~ Famiy Guy
Cleveland ~ Ohh Peter, that tickles me in a way that if Loretta tickled me in that way, I'd say 'Oh yea, that's nice, that's the spot.'
Cleveland ~ I promised Loretta I'd trim the bushes then get tender with her.
by Cleveland Brown August 24, 2006