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1.
(taxes + toxicosis) - a seasonal depression caused by tax preparations; an acute condition of majority of population every March and April. Symptoms: weakness, exhaustion, nausea, melancholy, etc.

Cf. toxicosis, a pathological condition caused by the action of a poison or toxin.
You look a sort of depressed. What happened? - A usual spring condition: taxicosis.
by Mikhail Epstein March 30, 2008