Besides it's actual meaning, there was an oldschool rapper named Syke. He was one of Tupac Shakur's greatest friends and appeared in serveral of his songs. He's most famous for singing in 2Pac's songs "Picture Me Rollin'" and "How Long Will They Mourn Me?"
So day after day, ride after ride, we'll all hook up on the other side. Watch over your family and your newborn. Till we meet again homie.
A word used to establish that the previous statement was false, usually followed by laughing. This is usually used when the user is unsure weather or not the joke was realised or wants to make it apparent that he or she was using sarcasm.
Dude that's some cool car you have...syke! XD Bahahahaha