Top Definition
The low energy and depression you feel when you cycle off of bodybuilding supplements high in caffeine, L-arginine and B vitamins. This is due to the fact that once you train with supplements, you cant train without them.
me: "ughh I'm soo tired bro. supplement withdrawal symptoms are the worst"
friend: "Did you stop taking NO-Xplode?"
me: "Yea, I just ran out"
friend: "Want some Jack3d bro?"
by Guerrero V Lopez January 13, 2012

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