substantia nigra 

A term used when upon entry into a party, a subtstantial amount of black people are seen within its limits.

(Also works some bullshit within the brain.)

There was mad substantia nigra last night, those bitches must have been looking to get bukkaked by the best of 'em.

substantia nigra by Sean "Droke" Hirst July 16, 2008

Substanize 

Swallowing, inhaling, snorting, or injecting yourself with a drug, usually one that is illegal without doctor shopping for a prescription first.

2 Strawz: You been movin bricks, $hasta?
$hasta: UOENO! Up for 24 hours with my lab coat on. Now I need to substanize my body with some alcohol STAT to wind the hell down.

Substanize by MrShasta June 6, 2013

substanisan

The word SUBSTANISAN was invented by the always adequite Lindsay Lohan . Nobody knows what does it really mean therefore you can spot many different usages.

Whoa, that would be more than substanisan!

Oh my gah, move to Substanisan already!

Substanisan my ... you moron!

I feel so substanisaned today.

Stop substanisantly substanisanting my substanisaned substanisan.

...Now repeat it over n over as quickly as you can!

substanisan by substanisanemigrant September 10, 2009

Substantial 

More than expected, surpasses expectations

How was that movie last night?

It was pretty substantial!

Substantial by S_C_A_B July 22, 2017

substantitive 

A bastardization of the word "substantive." Spoken by people who failed English class in high school.

I think we really had a substantitive debate tonight with Donald Trump not being in attendance. -Senator Rand Paul

substantitive by districtcraig October 14, 2016

substantial abundance of wiener

A term used to describe lot of guys in the same place; a sausage fest.

Phil: "What a rockin' club! Time to get my groove on!"
Matt: "Uh...I don't know man...there seems to be a substantial abundance of weiner in this joint."
Phil: "Whatever, I'm gonna go dance with that HOT girl over there!"
Matt: "No no wait dude, that's a..."
(Phil goes over to the "girl")
Phil: "You must be from Tennessee because there's a mirror in your pocket."
'Girl' (deep voice): "Just come here bitch!"
Phil: "Hey baby that cell phone in your pocket keeps jabbing me...let me fix that for you...wait a minute...what the...OH SHIT!!!" (runs away)
Matt (laughs hysterically)
Phil: "Damn, come to think of it, it was a little suspicious with all those effeminate guys dancing to the Village People in leather jackets."
Matt: "You grabbed a transvestite's dick, man."

substantial abundance of wiener by Nick D February 18, 2005

substantiate

To prove right because of proper evidence.
prove
solve

Sex is present in modern day society; TV substantiates my opinion.

substantiate by Adrian Ammsso November 29, 2004