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1. Someone who hasn't slept in over 24 hours. Normally, spazzed means that you have forcefully made yourself stay awake without any type of stimulant drug.

2. You can also use the word spazzed to define insomnia through your own definition of being awake for a long period of time.
Staying awake for a long time can make you have hallucinations.

"I haven't slept yet today."
"Damn, I bet you're pretty spazzed."
"Yeah, my eyes are playing tricks on me."
by Beautywreck June 11, 2008